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Semaglutide's GLP-1R selectivity distinguishes it from dual agonists (Tirzepatide GLP-1/GIP) or triple agonists (Retatrutide GLP-1/GIP/GCGR)
Serums & Treatments
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In the head-to-head SURMOUNT-5 trial, Zepbound produced significantly greater weight loss — an average of 20.2% versus 13.7% for Wegovy over 72 weeks, a 47% greater relative reduction
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