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Notably, PG-102 showed the lowest CD45⁺ area among groups, suggesting a possible trend toward reduced local inflammation compared to semaglutide or tirzepatide (Supplementary Fig
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Common side effects of tirzepatide include nausea (affecting 24-29% of participants in trials), diarrhea (18-24%), vomiting (8-10%), and constipation (16-17%)
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