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As part of ongoing patient assessment, healthcare providers should also ensure their patient is being treated with the optimum dose that achieves the best balance between efficacy, tolerability and acceptability [125]
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Moreover, studies conducted on animal models have shown that enteroendocrine L-cells increase the secretion of GLP-1 in response to inflammatory cytokines (e.g., interleukin-6 (IL-6) and lipopolysaccharide (LPS) (38)) and ischaemic injury (39)
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