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TGR5 Activation Modulates an Inhibitory Effect on Liver Fibrosis Development Mediated by Anagliptin in Diabetic Rats

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Pancreatic β-Cell Protection and Function In pancreatic β-cells, GLP-1 receptor activation enhances glucose-stimulated insulin secretion by increasing intracellular cAMP production, which leads to protein kinase A phosphorylation and activation of exchange protein directly activated by cAMP (Epac)