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glp-1 patch reviews Patches Archives format-capsule Size:4 Oz The Clinical Application of
The Clinical Application of GLP-1RAs and GLP-1/GIP Dual Receptor Agonists Based on Pharmacological Mechanisms: A Review - PMC
The resolution to this debate likely depends on circuit-level neuroanatomy: a 2025 mouse study in Nature Metabolism by Gutgesell and colleagues, from the Muller and Tschop laboratory, independently showed that GIPR agonism and antagonism reduce body weight through distinct neuronal circuits, suggesting that the two strategies are not equivalent at a biological level even if they converge on similar body weight outcomes in some preclinical models
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doi: 10.1016/S0140-6736(15)00803-X