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Optimization of a novel series of fused β-homophenylalanine DPP-4 inhibitors was reported in detail by Jiang et al., leading to the development of β-homophenylalanine analogs containing pyrrolidin-2-yl methyl amides (123)

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"They're going to have to look at every single thing and trim dollars everywhere they can." Pennsylvania was looking for cost-saving strategies even before the new federal tax-and-spending law, according to Brandon Cwalina, press secretary for the state's Department of Human Services