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Dapagliflozin and the incidence of type 2 diabetes in patients with heart failure and reduced ejection fraction: an exploratory analysis from DAPA-HF
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Whilst the effects of GLP-1 RA administration alone on lipogenesis have not been studied, co-administration of GLP-1 RA with glucagon reduces lipogenesis by lowering expression of β-hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase and sterol regulatory element-binding protein-1c (SBREBP-1C) [127]
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