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In the obese group, tirzepatide downregulated genes related to ErbB signaling and glycolysis/gluconeogenesis pathways, while increasing genes related to fatty acid degradation, cortisol synthesis/secretion, and B cell receptor signaling

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d-Allulose Inhibits Ghrelin-Responsive, Glucose-Sensitive and Neuropeptide Y Neurons in the Arcuate Nucleus and Central Injection Suppresses Appetite-Associated Food Intake in Mice