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Biotech Watchlist: Trevogrumab, A New Era in Obesity Management?
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In the colon, unabsorbed monosaccharides, polysaccharides, and non-digestible carbohydrates (fiber, resistant starch) are metabolized by bacterial fermentation into short-chain fatty acids [268,272] that bind free fatty acid receptors 2 and 3, resulting in GLP-1 secretion
