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GLP-1 made for US': Medanta founder Dr. Naresh Trehan explains risks for Indians using weight-loss drugs - The Economic Times

Furthermore, the exclusion of patients with CKD and using BMI in the PSM excluded and accounted for other indications for the use of GLP-1 RAs and ensured that their use in our patient population was for glycemic control

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The other long-term concern is muscle loss (sarcopenia), which is not drug specific – it accompanies any form of rapid weight reduction, and needs preventive measures like enhanced protein intake and strength training to be instituted from the beginning