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Polypharmacology is the basis for drug repurposing: this principle asserts that a drug with multiple targets can have multiple mechanisms of action ( Drug repositioning could indeed present several advantages as compared to the development of a new drug
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125 Moreover, research indicates that growth hormone enhances CYP3A4 expression in human hepatocytes, while synthetic somatostatin analogs like octreotide, which inhibit endogenous growth hormone, may decrease CYP3A4 activity
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