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In short, GLP-1 is an antidiabetogenic agent due to its action in the pancreas while acting in hypothalamic areas, helping to generate a state of satiety
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References: Impact of a Dual Glucose-Dependent Insulinotropic Peptide/Glucagon-Like Peptide-1 Receptor Agonist Tirzepatide on Heart Rate Among Patients With Type 2 Diabetes: A Systematic Review and Pairwise and Network Meta-Analysis
