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A total of 225 participants were included in the modified intention-to-treat population and assigned to tirzepatide 10 mg ( n = 73), 15 mg ( n = 77), or placebo ( n = 75), alongside lifestyle modifications
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Impairment of mitochondrial function and structure is closely associated with HF, while disruption of glucolipid metabolism and mitochondrial damage can influence each other 37
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