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When semaglutide, a GLP-1 receptor agonist, circulates in the bloodstream, it does not just act on the pancreas and the brain
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butyricum upregulates IFN-λ production by inducing the ω-3 fatty acid 18-hydroxy eicosapentaenoic acid (18-HEPE), which activates G protein-coupled receptor 120(GPR120) and interferon regulatory factors (IRF-1 and IRF-7) (34, 35)
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