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The UK medicines regulator, the MHRA, has updated the product information for healthcare professionals and patients regarding the "small risk of severe acute pancreatitis in patients taking GLP-1s." While rare, the sheer scale of GLP-1 use in the UK – with one recent study suggesting 1.6 million adults had used them in the last 12 months, and 3.3 million were interested in trying them in the following year – makes it important for clinicians and patients to be aware of the warning signs of pancreatitis, said the regulator

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