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Dopamine plays a prominent role in the immediate reinforcing/rewarding effects of drugs—‘the dopamine theory’, and dysregulation of the dopamine system is thought to contribute to the addicted state as a predisposing factor and/or a consequence of chronic substance use (Volkow, Michaelides, et al., 2019)
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References 1 RivaASahinEVolpedoGCataniaNTVenaraIBiagioliVet al