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Trulicity Cardiovascular Data (REWIND Trial) The REWIND trial studied dulaglutide in patients with Type 2 diabetes: Study population: 9,901 patients with Type 2 diabetes, broader population including those without prior cardiovascular events Results: 12% reduction in major adverse cardiovascular events (MACE) Statistically significant cardiovascular protection Benefit seen in both primary and secondary prevention Ozempic Cardiovascular Data (SUSTAIN 6 and SELECT) SUSTAIN 6 trial (diabetes population): 26% reduction in MACE in patients with Type 2 diabetes and high cardiovascular risk Significant cardiovascular protection SELECT trial (obesity population): 20% reduction in MACE in patients with obesity and established cardiovascular disease Studied for cardiovascular outcomes regardless of diabetes status Cardiovascular Comparison Both medications provide cardiovascular protection
