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Absolute contraindications: Active malignancy — IGF-1 is mitogenic and promotes cell growth Pregnancy Disruption of the hypothalamic-pituitary axis by injury, tumor, or surgery Hypersensitivity to tesamorelin or mannitol (an excipient in the formulation) A qualified metabolic provider will screen for all of these before initiating therapy
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Utilizing post-marketing data, this research compares patients prescribed GLP-1 RAs (cases) with those not taking these medications (controls)
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