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Cagrilintide monotherapy uses up to 4.5 mg weekly, while retatrutide reaches 12 mg weekly, but combining these maximum doses would almost certainly be unsafe
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Pooled analysis from eight cohort studies estimated that GLP-1 RA therapy increases the relative risk of inadequate cleansing by 80%, yielding a number needed to repeat (NNR) of just 14 colonoscopies [23]
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