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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Koychev I., Adler A.I., Edison P., Tom B., Milton J.E., Butchart J., Hampshire A., Marshall C., Coulthard E., Zetterberg H., et al

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Taking a second dose too soon creates drug accumulation that significantly increases both the likelihood and severity of side effects, particularly the gastrointestinal ones

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