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Iron deficiency anemia typically prolongs red blood cell lifespan and increases cumulative glycation exposure, leading to a falsely elevated HbA1c, whereas conditions associated with shortened erythrocyte survival—such as hemolysis or acute blood loss—result in falsely lowered HbA1c values

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However, alongside the medical benefits of weight reduction , an increasing number of patients and clinicians are encountering a visible and often distressing side effect : facial volume loss, popularly termed Ozempic face