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In humans, GLP-1Rs are found in a variety of tissues, including pancreatic islets, the lungs, the kidneys, the gastrointestinal tract, the central nervous system, the vagus nerve, endothelial cells and smooth muscle cells, as well as in atrial and ventricular cardiomyocytes
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Importantly, the FDA stated in the Motion that it will not take enforcement action against 503Bs for compounding tirzepatide as they did while the drug was on the FDA shortage list
