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“But I’m having a really good experience with it and I wanted to keep it real with you about that.” December 2025 Schumer addressed her followers’ reactions to losing weight on social media, noting that she didn’t do it to “look hot” but rather “to survive.” “I had a disease that makes your face extremely puffy that can kill you but the internet caught it and that disease has been cleared,” Schumer said via Instagram Video referring to being diagnosed with Cushing syndrome in February 2024

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Who may be considered for treatment and who may need caution Retatrutide is being studied primarily for adults with obesity or overweight linked to metabolic complications