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Libu Varughese, an endocrinologist shared, “GLP-1 [glucagon-like peptide] is a naturally occurring hormone that helps regulate blood sugars, diet, and appetite.” Prescription drugs like Ozempic are “GLP-1 agonists” that mimic this hormone and “help with both weight and diabetes management by slowing down stomach activity, causing insulin to more efficiently reduce blood sugar levels.” Varughese adds that these medications enhance feelings of fullness, contributing to greater weight loss and glycaemic control
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Indeed, enteric neurons express GLP-1Rs, and primary cultures of myenteric neurons have increased neuronal activation following GLP-1 treatment 73
