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GLP-1 Receptor Agonists in the Treatment of Patients with Type 2 Diabetes and Chronic Kidney Disease
Notably, a 1-week treatment with 200 μg/kg liraglutide exacerbated bleomycin-induced lung injury in control but not Glp1r –/– mice, an effect prevented by cotreatment with atipamezole, an α 2 -adrenergic receptor antagonist
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Endocrinologist Daniel Drucker says that the trials were well-done but the results are “a setback for the field.” Novo Nordisk confirmed in a statement to Scientific American that the company is ending its semaglutide trials on Alzheimer’s, including tests involving the injectable version of the drug