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Lilly's 2025 guidance of USD 58–61 billion implies continued 32% growth momentum, validated by the SURMOUNT-5 Phase 3b head-to-head trial result: Zepbound demonstrated 47% greater relative weight loss compared to Wegovy — the most commercially consequential head-to-head data in the obesity market

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GLP-1 Pipeline Update: August 2025 Quarterly view of the GLP-1 pipeline and anticipated indications Editorial team Maryam Tabatabai, PharmD Editor-In-Chief Associate Vice President, Clinical Information Carole Kerzic, RPh Executive Editor Drug Information Pharmacist Principal Nicole Kjesbo, PharmD, BCPS Executive Editor Clinical Program Development Director Senior, Pipeline DISCLAIMER The drug pipeline is fluid

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