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Symptoms may also be exacerbated in perimenopause when oestrogen may fluctuate from high to low and there may be anovulatory cycles
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Another study showed that, while satiety hormones CCK and PYY induce acute reaction of AgRP+ neurons after infusion, these effects take on the order of minutes, not seconds, to induce neuronal changes (Beutler et al., 2017)
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