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Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin in type 2 diabetes mellitus (LEAD-2 Met)
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Glucagon secretion from α cells is also inhibited proportionally to the glucose concentration, which is considered to be mediated by an increase in insulin or somatostatin secretion or by an inhibitory effect via the vagus nerve
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