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As a modified version of the naturally occurring GLP-1 hormone, semaglutide has a 94% amino acid sequence homology to human GLP-1 but includes strategic modifications that extend its half-life to approximately one week, enabling once-weekly dosing
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[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Frías J.P., Davies M.J., Rosenstock J., Pérez Manghi F.C., Fernández Landó L., Bergman B.K., Liu B., Cui X., Brown K
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