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The British National Formulary (BNF) does not list a specific interaction between semaglutide and bupropion, which provides reassurance regarding their concurrent use

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La Sociedad Española de Médicos Generales y de Familia advierte de que, a pesar de que se trata de medicamentos sujetos a prescripción médica, se ha producido un incremento notable en su demanda al producir una pérdida notable de peso