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In pancreatic islet models, this signaling induces glucose-dependent insulin secretion while suppressing inappropriately high glucagon release under hyperglycemia

PENDULUM

Option:Semaglutide Program + Hormone Wellness Test

Participants were randomized to receive weekly subcutaneous retatrutide at doses of 1 mg, 4 mg, 8 mg, or 12 mg, or placebo, for 48 weeks