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Endothelial cells (ECs) are considered innate immune cells depending on their different immunological characteristics and functions, such as endothelial plasticity, expression of different pattern recognition receptors (PRRs), cytokine and chemokine release, direct interaction with different immune cells and serving as antigen-presenting cells to T cells [38,202,203]
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Legal questions swirl around FDA’s new expedited drug program, including who should sign off Legal questions swirl around FDA’s new expedited drug program, including who should sign off WASHINGTON (AP) — The Food and Drug Administration commissioner’s effort to drastically shorten the review of drugs favored by President Donald Trump’s administration is causing alarm across the agency, stoking worries that the plan may run afoul of legal, ethical and scientific standards long used to vet the safety and effectiveness of new medicines