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Researchers also watch for counter-regulatory responses—e.g., glucagon-driven gluconeogenesis offsetting insulin-mediated uptake—so net outcomes are interpreted in context
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In fasted healthy normal weight patients, GLP-1 (7-36) amide injection reduced fMRI activity induced by food images, in all brain areas studied (amygdala, insula, caudate, NAc, orbitofrontal cortex, and putamen), compared to saline injection [43]
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