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Long-acting release formulation of exenatide (Microspheres) Polymer materials commonly used in microsphere preparation are polylactic-co-glycolic acid (PLGA), which is approved by FDA and has good safety and biodegradability
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doi:10.1056/NEJMoa2301972 Coskun T, Urva S, Roell WC, Qu H, Loghin C, Moyers JS, O'Farrell LS, Briere DA, Sloop KW, Thomas MK, Pirro V, Wainscott DB, Willard FS, Abernathy M, Morford L, Du Y, Benson C, Gimeno RE, Haupt A, Milicevic Z