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or very rapid heartbeat." Other situations that require emergency care include: Widespread hives affecting multiple areas of your body Blisters in sensitive areas like your mouth, eyes, or genitals High fever combined with severe pain at the injection site Sudden, intense abdominal pain radiating to your back (a potential sign of pancreatitis) Swelling of your tongue or throat that makes breathing difficult Don’t hesitate to act if you notice any of these symptoms – quick action can be lifesaving