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[20] [21] NICE guidance supports orlistat use as part of a comprehensive weight management programme for adults with a BMI of 28 kg/m² or above with associated risk factors (such as type 2 diabetes or cardiovascular disease), or 30 kg/m² or above without additional risk factors

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Using a predetermined dose instead of adjusting the amount based on your response to the anesthetic can lead to more side effects from the drug