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Losing 15% of your body weight improves blood pressure, cholesterol, blood sugar, joint pain, sleep apnea, and overall quality of life regardless of which medication gets you there

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“It’s likely due to the drug itself having what we call ‘weight-independent effects’ on cardiovascular events, things like reduced inflammation and improved vasculature and kidney health, all these other beneficial effects that have to do with reducing the development another cardiovascular event,” Kushner said