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Transgenic lines overexpressing proteins such as amyloid precursor protein/presenilin‐1 (APP/PS1) or Tau‐P301S or carrying deletions in innate immunity regulators like triggering receptor expressed on myeloid cells 2 (TREM2) and NOD‐, LRR‐, and pyrin domain‐containing protein 3 (NLRP3), have been instrumental in dissecting glial and neuronal responses within the inflamed brain
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Berberine is a compound found in parts of plants in the Berberidaceae family, including European barberry, goldenseal, and tree turmeric
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