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Tirzepatide: a new low for bodyweight and blood glucose - The Lancet Diabetes & Endocrinology

These include the modulation of the TME, interference with resistance-associated signalling pathways (e.g., phosphatidylinositol 3-kinase PI3K/Akt), and possible synergistic effects with chemotherapy

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Gastrointestinal adverse events of tirzepatide in the treatment of type 2 diabetes mellitus: a meta-analysis and trials sequential analysis