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Several scientific studies have found that taking Wegovy and other GLP-1 drugs increases someone’s chances of developing a debilitating eye condition called NAION (non-arteritic Anterior Ischemic Optic Neuropathy)

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Another GLP-1 analogue, lixisenatide, was reported to prevent the acuteness of cardiovascular events in apolipoprotein E −/− insulin receptor substrate 2 +/− (APOE −/− irs2 +/− ) mice by reducing the size of AS plaques, increasing plaque stability, and promoting the conversion of macrophages to the anti-inflammatory M2 phenotype (129)