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Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms of action | Nature Reviews Cardiology

The medication works by enhancing the activity of GABA, a neurotransmitter that calms brain signals, and blocking carbonic anhydrase enzymes that affect neural function

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GLP-1 receptor agonists like Zepbound (tirzepatide) and Wegovy (semaglutide) work by mimicking natural hormones that regulate appetite, blood sugar, and metabolism