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SGLT2 inhibitors are preferred in people with HF or at high-risk for HF, whereas GLP-1 receptor agonists are favored for those requiring significant weight loss, ASCVD risk reduction, CKD management, or in whom mitigation of metabolic dysfunction-associated steatotic liver disease (MASLD) or steatohepatitis is a clinical priority [84]
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Importantly, patients should not discontinue GLP-1 therapy without medical guidance, as the benefits for diabetes management or weight loss typically outweigh the temporary inconvenience of hair shedding
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