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Gallbladder problems (like gallstones): pain in your upper stomach, fever, yellowing of the skin or eyes, or clay-coloured stools

Heart

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Important safety considerations include a boxed warning for thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), and warnings for pancreatitis, gallbladder disease, acute kidney injury, and severe gastrointestinal disease