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Semaglutide works for weight loss by mimicking the action of incretin, a natural gut hormone called GLP-1, and targeting GLP-1 receptors in the brain that control appetite and slow down how quickly the stomach empties, making you feel fuller for longer

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Statistical analysis was conducted using IBM SPSS V.26.0, and the “mediation” package in R V.4.1.2 was applied for mediation analysis in this study