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The percentage of cells value was set to 0.25, the natural log fold-change threshold was set to 0.1 with an adjusted P value threshold set to 0.05 for both ligand and receptor
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Meet the weight-management clinical criteria (measured at the time GLP-1 therapy was first started): BMI of 35 or higher, or BMI of 30 or higher with heart failure (preserved ejection fraction), uncontrolled high blood pressure, or chronic kidney disease (stage 3a or above), or BMI of 27 or higher with prediabetes, a previous heart attack, a previous stroke, or symptomatic peripheral artery disease