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Therefore, drugs with a potent antihyperglycemic effect, independent of the glomerular filtration rate, with a low risk of hypoglycemia, that reduce weight in overweight/obese patients and that provide cardiovascular and renal protection, such as GLP-1 receptor agonists, are needed

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Ongoing research highlights the significant clinical potential of incretin-based therapies, especially in emerging areas such as central nervous system disorders, substance use, and post-transplant care

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