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When comparing metabolic parameters pre and post the 2-week treatment, we observed that liraglutide significantly lowered fat mass in male WT mice, however similar changes failed to reach statistical significance in female WT mice ( Figure 2E )

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2 The mechanism of action of kratom is suspected to involve agonism of multiple opioid receptors, stimulation of adrenergic receptors, and somewhat undetermined actions on serotonin and dopamine receptors