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This would likely reintroduce the mechanical stress and “metabolic fire” that caused the initial discomfort, potentially restarting the “weight-pain” cycle
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Once‐weekly tirzepatide versus once‐daily insulin degludec as add‐on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS‐3): a randomised, open‐label, parallel‐group, phase 3 trial