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⸻ ⚡ Takeaway: For HFpEF patients with obesity + T2D, GLP-1s and dual agonists are emerging not only as metabolic therapies but as cardiovascular disease-modifying agents
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GCG104 exhibits potent body-weight lowering effects with daily administration at 7.5 nmole/kg over the course of 12 days, an effect ultimately reliant on whole-body glucagon receptor expression, and more specifically hepatic glucagon receptor expression [80]
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