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En América Latina la mayoría de la causalidad atribuible es dada, además, del tabaquismo, por: obesidad abdominal, dislipidemia, hipertensión arterial y Diabetes Mellitus tipo 2 (DM2), conjunto de alteraciones que conforman el denominado Síndrome Metabólico y que en Latinoamérica es de particular importancia por su alta prevalencia que llega a ser de más del 35%3